Voclosporin as a treatment for noninfectious uveitis.

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Schultz C

Voclosporin as a treatment for noninfectious uveitis.

Ophthalmol Eye Dis. 2013 May 5;5:5-10. doi: 10.4137/OED.S7995. Print 2013.

PubMed ID

23700374 [ View in PubMed

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Abstract

Voclosporin is a relatively new calcineurin inhibitor that has been used successfully in humans for the treatment of plaque psoriasis. Available data indicate a good safety profile for this treatment and a significant increase in quality of life for psoriasis patients. More recently, voclosporin has been used to treat ophthalmic conditions such as uveitis. The limited data available indicate at least comparable results relative to current therapy with a better safety profile. Here, we analyze data from human and animal studies and the mode of action of voclosporin. Available safety profile data are also discussed.

DrugBank Data that Cites this Article

Drugs

Voclosporin

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
Voclosporin	Calcium signal-modulating cyclophilin ligand	Protein	Humans	Yes	Binder	Details