Xylometazoline nasal drops induced anaphylaxis: An atypical perioperative complication.

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Haldar R, Bajwa SS, Kaur J

Xylometazoline nasal drops induced anaphylaxis: An atypical perioperative complication.

J Anaesthesiol Clin Pharmacol. 2017 Jul-Sep;33(3):399-401. doi: 10.4103/0970-9185.173331.

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29109644 [ View in PubMed
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Abstract

Xylometazoline nasal drops used for nasal decongestion can have side-effect in the form of palpitation, hypertension, headache, and tremors. Anaphylaxis to xylometazoline nasal drops is a relatively unrecognized complication. We encountered a patient posted for tonsillectomy who developed serious anaphylaxis upon administration of a commercially available preparation of xylometazoline nasal drops and required aggressive management for stabilization. Further evaluation and literature search indicated toward the preservative (benzylalkonium chloride) as the cause of this adverse event.

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