Essentials of local anesthetic pharmacology.

Article Details

Citation

Becker DE, Reed KL

Essentials of local anesthetic pharmacology.

Anesth Prog. 2006 Fall;53(3):98-108; quiz 109-10. doi: 10.2344/0003-3006(2006)53[98:EOLAP]2.0.CO;2.

PubMed ID
17175824 [ View in PubMed
]
Abstract

It is impossible to provide effective dental care without the use of local anesthetics. This drug class has an impressive history of safety and efficacy, but all local anesthetics have the potential to produce significant toxicity if used carelessly. The purpose of this review is to update the practitioner on issues regarding the basic pharmacology and clinical use of local anesthetic formulations.

DrugBank Data that Cites this Article

Drugs
Drug Targets
DrugTargetKindOrganismPharmacological ActionActions
ChloroprocaineVoltage-gated sodium channel alpha subunit (Protein Group)Protein groupHumans
Yes
Inhibitor
Details
Drug Carriers
DrugCarrierKindOrganismPharmacological ActionActions
Benzocainealpha1-acid glycoprotein (Protein Group)Protein groupHumans
Unknown
Binder
Details