The anti-cancer activity of noscapine: a review.

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Mahmoudian M, Rahimi-Moghaddam P

The anti-cancer activity of noscapine: a review.

Recent Pat Anticancer Drug Discov. 2009 Jan;4(1):92-7. doi: 10.2174/157489209787002524.

PubMed ID
19149691 [ View in PubMed
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Abstract

Noscapine is an isoqiunoline alkaloid found in opium latex. Unlike most other alkaloids obtained from opium latex, noscapine is not sedative and has been used as antitussive drug in various countries. Recently, it has been introduced as an anti-mitotic agent. This drug can be used orally. When the resistance to other anti-cancer drugs such as paclitaxel manifests, noscapine might be effective. Therefore, noscapine and its analogs have great potential as novel anti-cancer agents.

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