Penbutolol and carteolol: two new beta-adrenergic blockers with partial agonism.

Article Details

Citation

Frishman WH, Covey S

Penbutolol and carteolol: two new beta-adrenergic blockers with partial agonism.

J Clin Pharmacol. 1990 May;30(5):412-21.

PubMed ID
2189902 [ View in PubMed
]
Abstract

Penbutolol and carteolol are two new long acting, nonselective beta-adrenergic blockers which have been approved for the treatment of systemic hypertension. Both drugs have intrinsic sympathomimetic activity (partial agonist activity), however, less than that seen with pindolol. They appear to cause less resting bradycardia than propranolol, have no effect on lipids and lipoproteins, and have favorable side effect profiles.

DrugBank Data that Cites this Article

Drugs
Drug Targets
DrugTargetKindOrganismPharmacological ActionActions
PenbutololBeta-1 adrenergic receptorProteinHumans
Yes
Antagonist
Partial agonist
Details
PenbutololBeta-2 adrenergic receptorProteinHumans
Yes
Antagonist
Partial agonist
Details