Penbutolol and carteolol: two new beta-adrenergic blockers with partial agonism.
Article Details
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Frishman WH, Covey S
Penbutolol and carteolol: two new beta-adrenergic blockers with partial agonism.
J Clin Pharmacol. 1990 May;30(5):412-21.
- PubMed ID
- 2189902 [ View in PubMed]
- Abstract
Penbutolol and carteolol are two new long acting, nonselective beta-adrenergic blockers which have been approved for the treatment of systemic hypertension. Both drugs have intrinsic sympathomimetic activity (partial agonist activity), however, less than that seen with pindolol. They appear to cause less resting bradycardia than propranolol, have no effect on lipids and lipoproteins, and have favorable side effect profiles.
DrugBank Data that Cites this Article
- Drugs
- Drug Targets
Drug Target Kind Organism Pharmacological Action Actions Penbutolol Beta-1 adrenergic receptor Protein Humans YesAntagonistPartial agonistDetails Penbutolol Beta-2 adrenergic receptor Protein Humans YesAntagonistPartial agonistDetails