Loperamide

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Sahi N, Nguyen R, Santos C

Loperamide

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PubMed ID

32491808 [ View in PubMed

]

Abstract

Loperamide is a medication used in the treatment of diarrhea. It classifies as an anti-diarrheal agent. The use of loperamide in high doses has been associated with a significant increase in morbidity and mortality. This activity reviews the indications, contraindications, activity, adverse events, and other key elements of loperamide abuse related to the essential points needed by members of an interprofessional team managing the care of patients with toxicity and its related conditions and sequelae.

DrugBank Data that Cites this Article

Drugs

Loperamide

Drug Transporters

Drug	Transporter	Kind	Organism	Pharmacological Action	Actions
Loperamide	P-glycoprotein 1	Protein	Humans	Unknown	Substrate	Details

Drug Interactions

• Approved
• Vet approved
• Nutraceutical
• Illicit
• Withdrawn
• Investigational
• Experimental
• All Drugs

Drugs	Interaction
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Loperamide Quinine	The excretion of Loperamide can be decreased when combined with Quinine.
Loperamide Toremifene	The excretion of Loperamide can be decreased when combined with Toremifene.
Loperamide Arsenic trioxide	The excretion of Loperamide can be decreased when combined with Arsenic trioxide.
Loperamide Paliperidone	The excretion of Loperamide can be decreased when combined with Paliperidone.
Loperamide Vandetanib	The excretion of Loperamide can be decreased when combined with Vandetanib.