Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications.

Article Details

Citation

Kador PF, Kinoshita JH, Sharpless NE

Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications.

J Med Chem. 1985 Jul;28(7):841-9.

PubMed ID
3925146 [ View in PubMed
]
Abstract

Not Available

DrugBank Data that Cites this Article

Drugs
Binding Properties
DrugTargetPropertyMeasurementpHTemperature (°C)
AlrestatinAldose reductaseIC 50 (nM)79000N/AN/ADetails
AlrestatinAldose reductaseIC 50 (nM)34000N/AN/ADetails
AlrestatinAldose reductaseIC 50 (nM)6500N/AN/ADetails
AlrestatinAldose reductaseIC 50 (nM)22000N/AN/ADetails
AlrestatinAldose reductaseIC 50 (nM)140000N/AN/ADetails
SorbinilAldose reductaseIC 50 (nM)700N/AN/ADetails
SorbinilAldose reductaseIC 50 (nM)2200000N/AN/ADetails
SorbinilAldose reductaseIC 50 (nM)1400000N/AN/ADetails
SorbinilAldose reductaseIC 50 (nM)7200N/AN/ADetails
SorbinilAldose reductaseIC 50 (nM)4700N/AN/ADetails