Effect of ibuprofen on bilirubin-albumin binding.
Article Details
- CitationCopy to clipboard
Ahlfors CE
Effect of ibuprofen on bilirubin-albumin binding.
J Pediatr. 2004 Mar;144(3):386-8.
- PubMed ID
- 15001951 [ View in PubMed]
- Abstract
Ibuprofen is used for closing the ductus arteriosus in premature newborn infants. Ibuprofen interferes with bilirubin-albumin binding and increases the unbound bilirubin in pooled newborn plasma to levels similar to those produced by sulfisoxazole, a drug that causes kernicterus in premature newborn infants.
DrugBank Data that Cites this Article
- Pharmaco-metabolomics
Drug Drug Groups Metabolite Change Description Sulfisoxazole Approved Vet Approved total bilirubin decreased Sulfisoxazole decreases the level of total bilirubin in the blood