Adenosine deaminase inhibitors. Conversion of a single chiral synthon into erythro- and threo-9-(2-hydroxy-3-nonyl)adenines.

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Bastian G, Bessodes M, Panzica RP, Abushanab E, Chen SF, Stoeckler JD, Parks RE Jr

Adenosine deaminase inhibitors. Conversion of a single chiral synthon into erythro- and threo-9-(2-hydroxy-3-nonyl)adenines.

J Med Chem. 1981 Dec;24(12):1383-5.

PubMed ID

7310814 [ View in PubMed

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Abstract

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DrugBank Data that Cites this Article

Binding Properties

Drug	Target	Property	Measurement	pH	Temperature (°C)
(2S,3R)-3-(6-amino-9H-purin-9-yl)nonan-2-ol	Adenosine deaminase	Ki (nM)	2	N/A	N/A	Details
Pentostatin	Adenosine deaminase	Ki (nM)	0.1	N/A	N/A	Details