Current landscape of phosphodiesterase 10A (PDE10A) inhibition.

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Chappie TA, Helal CJ, Hou X

Current landscape of phosphodiesterase 10A (PDE10A) inhibition.

J Med Chem. 2012 Sep 13;55(17):7299-331. doi: 10.1021/jm3004976. Epub 2012 Aug 14.

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22834877 [ View in PubMed

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DrugBank Data that Cites this Article

Binding Properties

Drug	Target	Property	Measurement	pH	Temperature (°C)
Mardepodect	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	IC 50 (nM)	0.3	N/A	N/A	Details
Papaverine	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	IC 50 (nM)	40	N/A	N/A	Details