Nonsteroidal inhibitors of human type I steroid 5-alpha-reductase.

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Jones CD, Audia JE, Lawhorn DE, McQuaid LA, Neubauer BL, Pike AJ, Pennington PA, Stamm NB, Toomey RE, Hirsch KS

Nonsteroidal inhibitors of human type I steroid 5-alpha-reductase.

J Med Chem. 1993 Feb 5;36(3):421-3.

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8381185 [ View in PubMed

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DrugBank Data that Cites this Article

Binding Properties

Drug	Target	Property	Measurement	pH	Temperature (°C)
Finasteride	3-oxo-5-alpha-steroid 4-dehydrogenase 1	IC 50 (nM)	62	N/A	N/A	Details
Finasteride	3-oxo-5-alpha-steroid 4-dehydrogenase 2	IC 50 (nM)	10	N/A	N/A	Details