Histone deacetylase inhibitors: from bench to clinic.

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Paris M, Porcelloni M, Binaschi M, Fattori D

Histone deacetylase inhibitors: from bench to clinic.

J Med Chem. 2008 Mar 27;51(6):1505-29. doi: 10.1021/jm7011408. Epub 2008 Feb 5.

PubMed ID
18247554 [ View in PubMed
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Abstract

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DrugBank Data that Cites this Article

Binding Properties
DrugTargetPropertyMeasurementpHTemperature (°C)
VorinostatHistone deacetylase 1IC 50 (nM)200N/AN/ADetails
VorinostatHistone deacetylase 1IC 50 (nM)21N/AN/ADetails
VorinostatHistone deacetylase 3IC 50 (nM)37N/AN/ADetails
VorinostatHistone deacetylase 6IC 50 (nM)25N/AN/ADetails