Synthesis of a red-shifted fluorescence polarization probe for Hsp90.
Article Details
- CitationCopy to clipboard
Moulick K, Clement CC, Aguirre J, Kim J, Kang Y, Felts S, Chiosis G
Synthesis of a red-shifted fluorescence polarization probe for Hsp90.
Bioorg Med Chem Lett. 2006 Sep 1;16(17):4515-8. Epub 2006 Jun 22.
- PubMed ID
- 16797988 [ View in PubMed]
- Abstract
The synthesis of a red-shifted cy3B-GM ligand and its evaluation as a fluorescence polarization probe for Hsp90 is presented.
DrugBank Data that Cites this Article
- Binding Properties
Drug Target Property Measurement pH Temperature (°C) 8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-2-Fluoro-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine Heat shock protein HSP 90-alpha EC 50 (nM) 1200 N/A N/A Details