Tamibarotene: AM 80, retinobenzoic acid, Tamibaro.

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Tamibarotene: AM 80, retinobenzoic acid, Tamibaro.

Drugs R D. 2004;5(6):359-62.

PubMed ID

15563242 [ View in PubMed

]

Abstract

Tamibarotene [AM 80, retinobenzoic acid, Amnoid, Tamibaro] is a novel synthetic retinoid that is in development with Nippon Shinyaku as a potential treatment for acute promyelocytic leukaemia (APL) and is pending approval in Japan. Tamibarotene was being developed by Shionogi in Japan but the company subsequently discontinued its involvement. Various nonindustrial sources, such as the University of Tokyo, Japan, have also played a role in the development of tamibarotene. Nippon Shinyaku has licensed the rights to tamibarotene from Toko Pharmaceutical Industries for the treatment of acute promyelocytic leukaemia, according to Nippon Shinyaku's June 2004 pipeline update. However it is unclear when Toko Pharmaceutical Industries acquired rights to the compound.

DrugBank Data that Cites this Article

Drugs

Tamibarotene

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
Tamibarotene	Retinoic acid receptor alpha	Protein	Humans	Yes	Agonist	Details
Tamibarotene	Retinoic acid receptor beta	Protein	Humans	Yes	Agonist	Details