Selective thyromimetics using receptor and tissue selectivity approaches: prospects for dyslipidemia.

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Joharapurkar AA, Dhote VV, Jain MR

Selective thyromimetics using receptor and tissue selectivity approaches: prospects for dyslipidemia.

J Med Chem. 2012 Jun 28;55(12):5649-75. doi: 10.1021/jm2004706. Epub 2012 May 1.

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22512468 [ View in PubMed

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DrugBank Data that Cites this Article

Binding Properties

Drug	Target	Property	Measurement	pH	Temperature (°C)
KB-141	Thyroid hormone receptor alpha	Ki (nM)	7.18	N/A	N/A	Details
KB-141	Thyroid hormone receptor beta	Ki (nM)	0.37	N/A	N/A	Details
Sobetirome	Thyroid hormone receptor beta	Kd (nM)	0.2	N/A	N/A	Details