Potential use of selective and nonselective Pim kinase inhibitors for cancer therapy.

Article Details

Citation

Copy to clipboard

Drygin D, Haddach M, Pierre F, Ryckman DM

Potential use of selective and nonselective Pim kinase inhibitors for cancer therapy.

J Med Chem. 2012 Oct 11;55(19):8199-208. doi: 10.1021/jm3009234. Epub 2012 Sep 4.

PubMed ID

22924342 [ View in PubMed

]

Abstract

Not Available

DrugBank Data that Cites this Article

Binding Properties

Drug	Target	Property	Measurement	pH	Temperature (°C)
6-(5-BROMO-2-HYDROXYPHENYL)-2-OXO-4-PHENYL-1,2-DIHYDROPYRIDINE-3-CARBONITRILE	Serine/threonine-protein kinase pim-1	IC 50 (nM)	50	N/A	N/A	Details
Quercetin	Serine/threonine-protein kinase pim-1	IC 50 (nM)	1100	N/A	N/A	Details