Inhibitors of farnesyltransferase: a rational approach to cancer chemotherapy?

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Bell IM

Inhibitors of farnesyltransferase: a rational approach to cancer chemotherapy?

J Med Chem. 2004 Apr 8;47(8):1869-78.

PubMed ID

15055985 [ View in PubMed

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Abstract

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DrugBank Data that Cites this Article

Binding Properties

Drug	Target	Property	Measurement	pH	Temperature (°C)
L-778123	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	IC 50 (nM)	2	N/A	N/A	Details
L-778123	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	EC 50 (nM)	6800	N/A	N/A	Details
Lonafarnib	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	IC 50 (nM)	1.9	N/A	N/A	Details