From the insoluble dye indirubin towards highly active, soluble CDK2-inhibitors.

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Jautelat R, Brumby T, Schafer M, Briem H, Eisenbrand G, Schwahn S, Kruger M, Lucking U, Prien O, Siemeister G

From the insoluble dye indirubin towards highly active, soluble CDK2-inhibitors.

Chembiochem. 2005 Mar;6(3):531-40.

PubMed ID

15742375 [ View in PubMed

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Abstract

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DrugBank Data that Cites this Article

Binding Properties

Drug	Target	Property	Measurement	pH	Temperature (°C)
5-Bromoindirubin	Cyclin-dependent kinase 2	IC 50 (nM)	1.00E+03	8	22	Details
5-Bromoindirubin	Cyclin-dependent kinase 2	IC 50 (nM)	8.00E+01	8	22	Details