Pharmacokinetics of coenzyme q10.

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Kalenikova EI, Gorodetskaya EA, Medvedev OS

Pharmacokinetics of coenzyme q10.

Bull Exp Biol Med. 2008 Sep;146(3):313-6.

PubMed ID
19240848 [ View in PubMed
]
Abstract

The pharmacokinetics of coenzyme Q10 powder and solution of solubilized form was studied after their oral administration to rats (10 mg/kg). Plasma concentrations of coenzyme Q10 were measured by HPLC with electrochemical detection over 48 hours. Solubilized coenzyme Q10 exhibited high absorption creating higher plasma concentrations of the drug, as a result of which its bioavailability constituted 264% of that for the powder.

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