Possible modes of action of the artemisinin-type compounds.

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Citation

Olliaro PL, Haynes RK, Meunier B, Yuthavong Y

Possible modes of action of the artemisinin-type compounds.

Trends Parasitol. 2001 Mar;17(3):122-6.

PubMed ID
11286794 [ View in PubMed
]
Abstract

Artemisinin-type compounds are used for the treatment of uncomplicated and severe forms of malaria. They reduce parasitaemia more rapidly than any other antimalarial compound known, and are effective against multidrug-resistant parasites. However, uncertainties remain as to how they act on the parasite and cause toxicity. In this review, we summarize current ideas.

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