How long will I be blue? Prolonged skin staining following sentinel lymph node biopsy using intradermal patent blue dye.

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Gumus M, Gumus H, Jones SE, Jones PA, Sever AR, Weeks J

How long will I be blue? Prolonged skin staining following sentinel lymph node biopsy using intradermal patent blue dye.

Breast Care (Basel). 2013 Jun;8(3):199-202. doi: 10.1159/000352092.

PubMed ID

24415970 [ View in PubMed

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Abstract

BACKGROUND: Blue dye used for sentinel lymph node biopsy (SLNB) in breast cancer patients may cause prolonged skin discoloration at the site of injection. The aim of this study was to assess the duration of such skin discoloration. PATIENTS AND METHODS: 236 consecutive patients who had undergone breast conserving surgery and SLNB for breast cancer were reviewed prospectively from January 2007 to December 2009. RESULTS: Of the 236 patients, 2 had undergone bilateral surgery, and 41 had been examined in consecutive yearly reviews. Blue discoloration remained visible at the injection site after 12, 24, and > 36 months in 36.5, 23.6, and 8.6% of the patients, respectively. CONCLUSION: The use of patent blue for identification of the sentinel lymph node in patients undergoing breast cancer surgery may result in prolonged discoloration of the skin at the injection site.

DrugBank Data that Cites this Article

Drugs

Patent Blue

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
Patent Blue	Serum albumin	Protein	Humans	Yes	Binder	Details