Antarelix (EP 24332) a novel water soluble LHRH antagonist.

Article Details

Citation

Deghenghi R, Boutignon F, Wuthrich P, Lenaerts V

Antarelix (EP 24332) a novel water soluble LHRH antagonist.

Biomed Pharmacother. 1993;47(2-3):107-10.

PubMed ID
7693007 [ View in PubMed
]
Abstract

A novel water soluble LHRH antagonist (EP 24332-Antarelix) is described. Its activity in vitro and in vivo in several animal models is given. Antarelix (Ac-D-Nal, D-Cpa, D-Pal, Ser, Tyr, D-Hci, Leu, Lys-(iPr), Pro, D-Ala-NH2) in view of its potency, modest histamine-liberating activity and high water solubility has been selected for further development.

DrugBank Data that Cites this Article

Drug Targets
DrugTargetKindOrganismPharmacological ActionActions
TeverelixGonadotropin-releasing hormone receptorProteinHumans
Yes
Antagonist
Details