Genetics of a multifactorial disease: autoimmune type 1 diabetes mellitus.

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Cornall RJ

Genetics of a multifactorial disease: autoimmune type 1 diabetes mellitus.

Clin Sci (Lond). 1993 Mar;84(3):257-62.

PubMed ID
8384947 [ View in PubMed
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Abstract

1. Three non-major histocompatibility complex genes, Idd-3, Idd-4 and Idd-5, that influence the onset of autoimmune type 1 diabetes in the non-obese diabetic mouse have been located on chromosomes 3, 11 and 1. 2. In undertaking this study, a new map of the mouse genome has been created from polymerase chain reaction-analysable mouse microsatellite markers. 3. The homologues of these genes may reside on human chromosomes 1 or 4 (Idd-3), 17 (Idd-4) and 2q (Idd-5).

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