Hypokalemia: a clinical update.

Article Details

Citation

Kardalas E, Paschou SA, Anagnostis P, Muscogiuri G, Siasos G, Vryonidou A

Hypokalemia: a clinical update.

Endocr Connect. 2018 Apr;7(4):R135-R146. doi: 10.1530/EC-18-0109. Epub 2018 Mar 14.

PubMed ID
29540487 [ View in PubMed
]
Abstract

Hypokalemia is a common electrolyte disturbance, especially in hospitalized patients. It can have various causes, including endocrine ones. Sometimes, hypokalemia requires urgent medical attention. The aim of this review is to present updated information regarding: (1) the definition and prevalence of hypokalemia, (2) the physiology of potassium homeostasis, (3) the various causes leading to hypokalemia, (4) the diagnostic steps for the assessment of hypokalemia and (5) the appropriate treatment of hypokalemia depending on the cause. Practical algorithms for the optimal diagnostic, treatment and follow-up strategy are presented, while an individualized approach is emphasized.

DrugBank Data that Cites this Article

Drugs
Drug Targets
DrugTargetKindOrganismPharmacological ActionActions
PotassiumSodium/potassium-transporting ATPase subunit alpha-1ProteinHumans
Unknown
Regulator
Details
Drug Transporters
DrugTransporterKindOrganismPharmacological ActionActions
PotassiumSodium/potassium-transporting ATPase subunit alpha-1ProteinHumans
Unknown
Substrate
Details
Drug Interactions
DrugsInteraction
Olodaterol
Caffeine
Caffeine may increase the hyperkalemic activities of Olodaterol.
Olodaterol
Theophylline
Theophylline may increase the hyperkalemic activities of Olodaterol.
Olodaterol
Dyphylline
Dyphylline may increase the hyperkalemic activities of Olodaterol.
Olodaterol
Pentoxifylline
Pentoxifylline may increase the hyperkalemic activities of Olodaterol.
Olodaterol
Mercaptopurine
Mercaptopurine may increase the hyperkalemic activities of Olodaterol.