The Importance of Magnesium in Clinical Healthcare.
Article Details
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Schwalfenberg GK, Genuis SJ
The Importance of Magnesium in Clinical Healthcare.
Scientifica (Cairo). 2017;2017:4179326. doi: 10.1155/2017/4179326. Epub 2017 Sep 28.
- PubMed ID
- 29093983 [ View in PubMed]
- Abstract
The scientific literature provides extensive evidence of widespread magnesium deficiency and the potential need for magnesium repletion in diverse medical conditions. Magnesium is an essential element required as a cofactor for over 300 enzymatic reactions and is thus necessary for the biochemical functioning of numerous metabolic pathways. Inadequate magnesium status may impair biochemical processes dependent on sufficiency of this element. Emerging evidence confirms that nearly two-thirds of the population in the western world is not achieving the recommended daily allowance for magnesium, a deficiency problem contributing to various health conditions. This review assesses available medical and scientific literature on health issues related to magnesium. A traditional integrated review format was utilized for this study. Level I evidence supports the use of magnesium in the prevention and treatment of many common health conditions including migraine headache, metabolic syndrome, diabetes, hyperlipidemia, asthma, premenstrual syndrome, preeclampsia, and various cardiac arrhythmias. Magnesium may also be considered for prevention of renal calculi and cataract formation, as an adjunct or treatment for depression, and as a therapeutic intervention for many other health-related disorders. In clinical practice, optimizing magnesium status through diet and supplementation appears to be a safe, useful, and well-documented therapy for several medical conditions.
DrugBank Data that Cites this Article
- Drugs
- Drug Interactions
Drugs Interaction Integrate drug-drug
interactions in your softwareMagnesiumTetracycline The serum concentration of Magnesium can be decreased when it is combined with Tetracycline. MagnesiumMinocycline The serum concentration of Magnesium can be decreased when it is combined with Minocycline. MagnesiumAmiodarone The serum concentration of Magnesium can be decreased when it is combined with Amiodarone. MagnesiumPhenytoin The serum concentration of Magnesium can be decreased when it is combined with Phenytoin. MagnesiumPhenobarbital The serum concentration of Magnesium can be decreased when it is combined with Phenobarbital.