Immunological mechanisms of vaccination.

Article Details

Citation

Pulendran B, Ahmed R

Immunological mechanisms of vaccination.

Nat Immunol. 2011 Jun;12(6):509-17. doi: 10.1038/ni.2039.

PubMed ID
21739679 [ View in PubMed
]
Abstract

Vaccines represent one of the greatest triumphs of modern medicine. Despite the common origins of vaccinology and immunology more than 200 years ago, the two disciplines have evolved along such different trajectories that most of the highly successful vaccines have been made empirically, with little or no immunological insight. Recent advances in innate immunity have offered new insights about the mechanisms of vaccine-induced immunity and have facilitated a more rational approach to vaccine design. Here we will discuss these advances and emerging themes on the immunology of vaccination.

DrugBank Data that Cites this Article

Drugs
Drug Interactions
DrugsInteraction
Adenovirus type 7 vaccine live
Ozanimod
The therapeutic efficacy of Adenovirus type 7 vaccine live can be decreased when used in combination with Ozanimod.
Adenovirus type 7 vaccine live
Fingolimod
The therapeutic efficacy of Adenovirus type 7 vaccine live can be decreased when used in combination with Fingolimod.
Anthrax vaccine
Ozanimod
The therapeutic efficacy of Anthrax vaccine can be decreased when used in combination with Ozanimod.
Anthrax vaccine
Fingolimod
The therapeutic efficacy of Anthrax vaccine can be decreased when used in combination with Fingolimod.
Bacillus calmette-guerin substrain connaught live antigen
Ozanimod
The therapeutic efficacy of Bacillus calmette-guerin substrain connaught live antigen can be decreased when used in combination with Ozanimod.