Critical nodes in signalling pathways: insights into insulin action.

Article Details

Citation

Taniguchi CM, Emanuelli B, Kahn CR

Critical nodes in signalling pathways: insights into insulin action.

Nat Rev Mol Cell Biol. 2006 Feb;7(2):85-96.

PubMed ID
16493415 [ View in PubMed
]
Abstract

Physiologically important cell-signalling networks are complex, and contain several points of regulation, signal divergence and crosstalk with other signalling cascades. Here, we use the concept of 'critical nodes' to define the important junctions in these pathways and illustrate their unique role using insulin signalling as a model system.

DrugBank Data that Cites this Article

Polypeptides
NameUniProt ID
Insulin receptorP06213Details