Hb Luxembourg [alpha 24(B5) Tyr----His]: a new unstable variant.
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Groff P, Galacteros F, Kalmes G, Blouquit Y, Wajcman H
Hb Luxembourg [alpha 24(B5) Tyr----His]: a new unstable variant.
Hemoglobin. 1989;13(5):429-36.
- PubMed ID
- 2599879 [ View in PubMed]
- Abstract
Hb Luxembourg [alpha 24(B5)Tyr----His] was found in association with mild hemolytic anemia and increased indirect bilirubinemia in a family originating from the Netherlands. The slight instability of this variant may be the consequence of an indirect effect of the substitution on the alpha 1 beta 1 contact since position alpha 24 (B5) is internal and in contact with several residues involved in this interface.