Cloning and expression of human cDNA encoding Na+, K(+)-ATPase gamma-subunit.
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Kim JW, Lee Y, Lee IA, Kang HB, Choe YK, Choe IS
Cloning and expression of human cDNA encoding Na+, K(+)-ATPase gamma-subunit.
Biochim Biophys Acta. 1997 Feb 7;1350(2):133-5.
- PubMed ID
- 9048881 [ View in PubMed]
- Abstract
A cDNA clone encoding the Na+, K(+)-Atpase gamma-subunit polypeptide was cloned from a human fetal liver cDNA library. The deduced amino acid sequence of the protein comprised 58 amino acids with a calculated molecular weight of 6400 Da, and showed about 86% homology when compared with those of the bovine, rat and mouse Na+, K(+)-ATPase gamma-subunits published elsewhere. Northern blot analysis showed that the cDNA hybridized to a 0.7 kb mRNA which was expressed in human kidney, pancreas and fetal liver.