Screening and sequence determination of a cDNA encoding the human brain 4-aminobutyrate aminotransferase.
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Osei YD, Churchich JE
Screening and sequence determination of a cDNA encoding the human brain 4-aminobutyrate aminotransferase.
Gene. 1995 Apr 3;155(2):185-7.
- PubMed ID
- 7721088 [ View in PubMed]
- Abstract
A human brain cDNA library constructed in the lambda ZAP II vector was screened using a fragment of pig brain cDNA encoding 4-aminobutyrate aminotransferase (pGaba-t). A cDNA that encodes the human brain Gaba-t (hGaba-t) has been isolated from the library and sequenced. Using the GenBank and EMBL databases, comparison of the predicted amino-acid sequence of hGaba-t with the pig enzyme revealed 95.4% homology.