Beta-methylthio-aspartic acid: identification of a novel posttranslational modification in ribosomal protein S12 from Escherichia coli.

Article Details

Citation

Kowalak JA, Walsh KA

Beta-methylthio-aspartic acid: identification of a novel posttranslational modification in ribosomal protein S12 from Escherichia coli.

Protein Sci. 1996 Aug;5(8):1625-32.

PubMed ID
8844851 [ View in PubMed
]
Abstract

Utilizing microscale chemical derivatization reactions and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, we have identified a novel posttranslational modification of aspartic acid, beta-methylthio-aspartic acid. The modified residue is located at position 88 in ribosomal protein S12 from Escherichia coli, a phylogenetically conserved protein that has been implicated in maintaining translational accuracy of the ribosome.

DrugBank Data that Cites this Article

Polypeptides
NameUniProt ID
30S ribosomal protein S12P0A7S3Details