Focus on clozapine.

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Naheed M, Green B

Focus on clozapine.

Curr Med Res Opin. 2001;17(3):223-9.

PubMed ID
11900316 [ View in PubMed
]
Abstract

Clozapine is a dibenzodiazepine derivative and a truly atypical anti-psychotic. Its therapeutic effects are probably mediated by dopaminergic and serotonergic activity. Although it appears to be the most effective antipsychotic drug for treatment-resistant schizophrenia, its general use is limited because of the risk of agranulocytosis.

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