[The effect of inhibitors of sodium permeability (novocaine and tetrodotoxin) on the trace depolarization of myelinated nerve fibers].

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Katalymov LL

[The effect of inhibitors of sodium permeability (novocaine and tetrodotoxin) on the trace depolarization of myelinated nerve fibers].

Fiziol Zh Im I M Sechenova. 1995 Sep;81(9):127-33.

PubMed ID

8581044 [ View in PubMed

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Abstract

Partial block of the sodium permeability by local anesthetics does not induce significant aftereffect of depolarisation in intact Ranvier nodes of the frog isolated myelinated nerve fibres. The sodium current seems to take no part in generation of the depolarisation aftereffect.

DrugBank Data that Cites this Article

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
Procaine	Sodium channel protein type 10 subunit alpha	Protein	Humans	Yes	Inhibitor	Details