Human choline acetyltransferase (CHAT): partial gene sequence and potential control regions.

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Citation

Toussaint JL, Geoffroy V, Schmitt M, Werner A, Garnier JM, Simoni P, Kempf J

Human choline acetyltransferase (CHAT): partial gene sequence and potential control regions.

Genomics. 1992 Feb;12(2):412-6.

PubMed ID
1339386 [ View in PubMed
]
Abstract

Choline acetyltransferase (CHAT) (EC 2.3.1.6) is the biosynthetic enzyme for the neurotransmitter acetylcholine in the central and peripheral nervous systems. In this study, a human CHAT genomic clone has been isolated and partially sequenced at its 5' end. This fragment contains the first four exons with an ACG initiator codon and potential control regions including TATA, CAAT, GC boxes, and several transcription control sequences. A comparison of the primary structure of CHAT among pig, rat, mouse, and Drosophila is presented.

DrugBank Data that Cites this Article

Polypeptides
NameUniProt ID
Choline O-acetyltransferaseP28329Details