Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes.

Article Details


Burland V, Plunkett G 3rd, Sofia HJ, Daniels DL, Blattner FR

Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes.

Nucleic Acids Res. 1995 Jun 25;23(12):2105-19.

PubMed ID
7610040 [ View in PubMed

The 338.5 kb of the Escherichia coli genome described here together with previously described segments bring the total of contiguous finished sequence of this genome to > 1 Mb. Of 319 open reading frames (ORFs) found in this 338.5 kb segment, 147 (46%) are potential new genes. The positions of several genes which had been previously located here by mapping or partial sequencing have been confirmed. Several ORFs have functions suggested by similarities to other characterised genes but cannot be assigned with certainty. Fifteen of the ORFs of unknown function had been previously sequenced. Eight transfer RNAs are encoded in the region and there are two grey holes in which no features were found. The attachment site for phage P4 and three insertion sequences were located. The region was also analysed for chi sites, bend sites, REP elements and other repeats. A computer search identified potential promoters and tentative transcription units were assigned. The occurrence of the rare tetramer CTAG was analysed in 1.6 Mb of contiguous E.coli sequence. Hypotheses addressing the rarity and distribution of CTAG are discussed.

DrugBank Data that Cites this Article

NameUniProt ID
Fumarate reductase flavoprotein subunitP00363Details
3-keto-L-gulonate-6-phosphate decarboxylase UlaDP39304Details
Adenylosuccinate synthetaseP0A7D4Details
DNA mismatch repair protein MutLP23367Details
D-allose-binding periplasmic proteinP39265Details
Deoxyribose-phosphate aldolaseP0A6L0Details
Isoaspartyl dipeptidaseP39377Details
Fe(3+) dicitrate transport protein FecAP13036Details
HTH-type transcriptional regulator TreRP36673Details
Ornithine carbamoyltransferase chain IP04391Details
Divalent-cation tolerance protein CutAP69488Details
Thymidine phosphorylaseP07650Details
Purine nucleoside phosphorylase DeoD-typeP0ABP8Details
Soluble lytic murein transglycosylaseP0AGC3Details
2-iminobutanoate/2-iminopropanoate deaminaseP0AF93Details
Aspartate ammonia-lyaseP0AC38Details
Aspartate carbamoyltransferase catalytic subunitP0A786Details
Fumarate reductase iron-sulfur subunitP0AC47Details
Fumarate reductase subunit CP0A8Q0Details
Fumarate reductase subunit DP0A8Q3Details
tRNA dimethylallyltransferaseP16384Details
Probable L-ascorbate-6-phosphate lactonase UlaGP39300Details
Probable N-acetylneuraminic acid outer membrane channel protein NanCP69856Details