The use of apraclonidine eyedrops to treat ptosis after the administration of botulinum toxin to the upper face.

Article Details

Citation

Copy to clipboard

Scheinfeld N

The use of apraclonidine eyedrops to treat ptosis after the administration of botulinum toxin to the upper face.

Dermatol Online J. 2005 Mar 1;11(1):9.

PubMed ID

15748550 [ View in PubMed

]

Abstract

A side effect of the injection of botulinum toxin into the upper third of the face is ptosis or lid droop. A therapy recommended to treat ptosis resulting from administration of botulinum toxins A and B is Iopidine (apraclonidine 0.5 %) eye drops. Apraclonidine is an alpha2-adrenergic agonist, which causes Muller muscles to contract quickly elevating the upper eyelid 1-3 mm. Little published data discusses the use of apraclonidine to treat such ptosis. This communication discusses the extant literature on this usage. Research needs to be done to establish the utility and dosing of apraclonidine for botulinum toxin-induced ptosis.

DrugBank Data that Cites this Article

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
Apraclonidine	Alpha-2A adrenergic receptor	Protein	Humans	Yes	Agonist	Details