cDNA cloning of the beta-subunit of the human gastric H,K-ATPase.
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Ma JY, Song YH, Sjostrand SE, Rask L, Mardh S
cDNA cloning of the beta-subunit of the human gastric H,K-ATPase.
Biochem Biophys Res Commun. 1991 Oct 15;180(1):39-45.
- PubMed ID
- 1656976 [ View in PubMed]
- Abstract
A full-length cDNA clone encoding the human gastric H,K-ATPase (EC 3.6.1.36)beta-subunit was isolated from a human gastric mucosal lambda gt10 library using oligonucleotide probes which were based on the cDNA sequence from rat and rabbit H,K-ATPase beta-subunits. The insert was 1407 bp in length and encoded a polypeptide of 291 amino acids with a MW = 33,367 Da. It exhibited 84.2%, 85.6% and 81.3% identity to the H,K-ATPase beta-subunits of rabbit, pig and rat, respectively.