Use of variants of dihydrofolate reductase in gene transfer to produce resistance to methotrexate and trimetrexate.

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Bertino JR, Zhao SC, Mineishi S, Ercikan-Abali EA, Banerjee D

Use of variants of dihydrofolate reductase in gene transfer to produce resistance to methotrexate and trimetrexate.

Prog Exp Tumor Res. 1999;36:82-94.

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10386066 [ View in PubMed

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DrugBank Data that Cites this Article

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
Trimetrexate	Dihydrofolate reductase	Protein	Humans	Yes	Inhibitor	Details