Sequence and expression of human GABAA receptor alpha 1 and beta 1 subunits.
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Schofield PR, Pritchett DB, Sontheimer H, Kettenmann H, Seeburg PH
Sequence and expression of human GABAA receptor alpha 1 and beta 1 subunits.
FEBS Lett. 1989 Feb 27;244(2):361-4.
- PubMed ID
- 2465923 [ View in PubMed]
- Abstract
The deduced amino acid sequences of cDNA clones encoding human GABAA receptor alpha 1 and beta 1 subunits are presented. The human subunits display very high levels of sequence identity with the corresponding bovine receptor subunits. The cloned human GABAA receptor subunits induce the formation of GABA-gated chloride channels when expressed in mammalian cells.