ST segment elevation induced by class IC antiarrhythmic agents: underlying electrophysiologic mechanisms and insights into drug-induced proarrhythmia.
Article Details
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Krishnan SC, Josephson ME
ST segment elevation induced by class IC antiarrhythmic agents: underlying electrophysiologic mechanisms and insights into drug-induced proarrhythmia.
J Cardiovasc Electrophysiol. 1998 Nov;9(11):1167-72.
- PubMed ID
- 9835260 [ View in PubMed]
- Abstract
Three patients in whom Class IC sodium channel blockers induced ST segment elevation in leads V1 through V3 are described. The underlying electrophysiologic mechanism, implications for drug-induced proarrhythmia, and the relationship of the finding to the Brugada syndrome type of idiopathic ventricular fibrillation are discussed.
DrugBank Data that Cites this Article
- Drug Targets
Drug Target Kind Organism Pharmacological Action Actions Encainide Sodium channel protein type 5 subunit alpha Protein Humans YesInhibitorDetails