A controlled comparative study of chlorprothixene vs. haloperidol in chronic schizophrenia.

Article Details

Citation

Fux M, Belmaker RH

A controlled comparative study of chlorprothixene vs. haloperidol in chronic schizophrenia.

Isr J Psychiatry Relat Sci. 1991;28(1):37-40.

PubMed ID
1830565 [ View in PubMed
]
Abstract

Neurochemical distinctions have been made between neuroleptic drugs that affect D-1 receptors as well as D-2 receptors, compared with those neuroleptic drugs that affect only D-2 receptors. However, a controlled double-blind study of haloperidol vs. chlorprothixene in schizophrenic patients found no significant differences.

DrugBank Data that Cites this Article

Drug Targets
DrugTargetKindOrganismPharmacological ActionActions
ChlorprothixeneDopamine D1 receptorProteinHumans
Yes
Antagonist
Details
ChlorprothixeneDopamine D2 receptorProteinHumans
Yes
Antagonist
Details
ChlorprothixeneDopamine D3 receptorProteinHumans
Yes
Antagonist
Details