Characterization of the human and mouse cDNAs coding for S100A13, a new member of the S100 protein family.

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Citation

Wicki R, Schafer BW, Erne P, Heizmann CW

Characterization of the human and mouse cDNAs coding for S100A13, a new member of the S100 protein family.

Biochem Biophys Res Commun. 1996 Oct 14;227(2):594-9.

PubMed ID
8878558 [ View in PubMed
]
Abstract

Here we report the characterization of the human S100A13 cDNA coding for a novel calcium-binding protein belonging to the S100 protein family. The predicted S100A13 protein shows sequence homologies to other S100 proteins between 50.5% (to S100A5) and 59.3% (to S100A12). High mRNA amounts were found in skeletal muscle, heart, kidney, ovary, small intestine and pancreas. Since twelve S100 genes are clustered on human chromosome 1q21, we determined the chromosomal localization of the human S100A13. It co-localizes with S100A1 on the cluster. Furthermore, we characterized the cDNA sequence coding for the mouse homolog of S100A13. Similar to the putative human protein, mouse S100A13 is composed of 98 amino acids displaying a homology of 86.7% compared to human S100A13.

DrugBank Data that Cites this Article

Polypeptides
NameUniProt ID
Protein S100-A13Q99584Details