Phototoxic and photoprotective effects of topical isothipendyl.

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Moreau A, Dompmartin A, Dubreuil A, Leroy D

Phototoxic and photoprotective effects of topical isothipendyl.

Photodermatol Photoimmunol Photomed. 1995 Apr;11(2):50-4.

PubMed ID

8546983 [ View in PubMed

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Abstract

Isothipendyl, an H1-receptor antagonist, is an antihistamine used as an antiallergic drug. Its molecular structure is close to the phenothiazines, but it has different photobiological properties. Like phenothiazines, isothipendyl is phototoxic with ultraviolet A (UVA) but it reduces the erythema response to UVB radiation. Isothipenyl seems to have the same protective properties as a sunscreen because its UVB protective properties are effective only if the substance is applied prior to exposure.

DrugBank Data that Cites this Article

Drugs

Isothipendyl

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
Isothipendyl	Histamine H1 receptor	Protein	Humans	Yes	Antagonist	Details