Evaluation of clorsulon against immature Fascioloides magna in cattle and sheep.

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Foreyt WJ

Evaluation of clorsulon against immature Fascioloides magna in cattle and sheep.

Am J Vet Res. 1988 Jul;49(7):1004-6.

PubMed ID
3421522 [ View in PubMed
]
Abstract

Efficacy of clorsulon was evaluated against infection with immature Fascioloides magna in 24 cattle and 12 sheep. Infections were induced by oral administration of 600 metacercariae/host. In cattle, clorsulon at dosages of 7 and 21 mg/kg of body weight was 65 and 100% effective against 8-week-old flukes, and 20 and 74% effective against 16-week-old flukes, respectively. In sheep, clorsulon at a dosage of 21 mg/kg was 92% effective against 8-week-old flukes. Significantly (P less than 0.05) more F magna were recovered from untreated sheep than from untreated cattle.

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