Molecular structure of the Japanese hepatitis C viral genome.
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Kato N, Hijikata M, Nakagawa M, Ootsuyama Y, Muraiso K, Ohkoshi S, Shimotohno K
Molecular structure of the Japanese hepatitis C viral genome.
FEBS Lett. 1991 Mar 25;280(2):325-8.
- PubMed ID
- 1849488 [ View in PubMed]
- Abstract
The amino acid sequence of the polyprotein deduced from the nucleotide sequence of the Japanese hepatitis C virus genome (N. Kato et al. (1990) Proc. Natl. Acad. Sci. USA 87, 9524-9528) indicated that this virus is a member of a new class of positive-stranded RNA viruses. Several domains of this polyprotein also showed weak homology with those of flaviviruses and pestiviruses including the chymotrypsin-like serine proteinase, NTPase and RNA-dependent RNA polymerase.