The gene yjfQ encodes the repressor of the yjfR-X regulon (ula), which is involved in L-ascorbate metabolism in Escherichia coli.

Article Details

Citation

Campos E, Aguilar J, Baldoma L, Badia J

The gene yjfQ encodes the repressor of the yjfR-X regulon (ula), which is involved in L-ascorbate metabolism in Escherichia coli.

J Bacteriol. 2002 Nov;184(21):6065-8.

PubMed ID
12374842 [ View in PubMed
]
Abstract

Mutations in yjfQ allowed us to identify this gene as the regulator of the operon yjfS-X (ula operon), reported to be involved in L-ascorbate metabolism. Inactivation of this gene renders constitutive the expression of the ula operon, indicating that YjfQ acts as a repressor. We also demonstrate that this repressor regulates the nearby yjfR gene, which in this way constitutes a regulon with the ula operon.

DrugBank Data that Cites this Article

Polypeptides
NameUniProt ID
3-keto-L-gulonate-6-phosphate decarboxylase UlaDP39304Details
Probable L-ascorbate-6-phosphate lactonase UlaGP39300Details