Evidence for lateral gene transfer between Archaea and bacteria from genome sequence of Thermotoga maritima.

Article Details

Citation

Nelson KE, Clayton RA, Gill SR, Gwinn ML, Dodson RJ, Haft DH, Hickey EK, Peterson JD, Nelson WC, Ketchum KA, McDonald L, Utterback TR, Malek JA, Linher KD, Garrett MM, Stewart AM, Cotton MD, Pratt MS, Phillips CA, Richardson D, Heidelberg J, Sutton GG, Fleischmann RD, Eisen JA, White O, Salzberg SL, Smith HO, Venter JC, Fraser CM

Evidence for lateral gene transfer between Archaea and bacteria from genome sequence of Thermotoga maritima.

Nature. 1999 May 27;399(6734):323-9.

PubMed ID
10360571 [ View in PubMed
]
Abstract

The 1,860,725-base-pair genome of Thermotoga maritima MSB8 contains 1,877 predicted coding regions, 1,014 (54%) of which have functional assignments and 863 (46%) of which are of unknown function. Genome analysis reveals numerous pathways involved in degradation of sugars and plant polysaccharides, and 108 genes that have orthologues only in the genomes of other thermophilic Eubacteria and Archaea. Of the Eubacteria sequenced to date, T. maritima has the highest percentage (24%) of genes that are most similar to archaeal genes. Eighty-one archaeal-like genes are clustered in 15 regions of the T. maritima genome that range in size from 4 to 20 kilobases. Conservation of gene order between T. maritima and Archaea in many of the clustered regions suggests that lateral gene transfer may have occurred between thermophilic Eubacteria and Archaea.

DrugBank Data that Cites this Article

Polypeptides
NameUniProt ID
L-lactate dehydrogenaseP16115Details
6-phospho-beta-glucosidase BglTQ9X108Details
Thymidylate synthase ThyXQ9WYT0Details
Chemotaxis protein CheAQ56310Details
4-hydroxy-tetrahydrodipicolinate synthaseQ9X1K9Details
Histidinol-phosphate aminotransferaseQ9X0D0Details
Holliday junction ATP-dependent DNA helicase RuvBQ56313Details
N-(5'-phosphoribosyl)anthranilate isomeraseQ56320Details
Bifunctional PGK/TIMP36204Details
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferaseQ9X112Details
4-alpha-glucanotransferaseP80099Details
Polyamine aminopropyltransferaseQ9WZC2Details
AminomethyltransferaseQ9WY54Details
Phospho-2-dehydro-3-deoxyheptonate aldolaseQ9WYH8Details
Cell division protein FtsZO08398Details
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferaseQ9X1B3Details
GTPase DerQ9X1F8Details
Phosphopantetheine adenylyltransferaseQ9WZK0Details
6-phosphogluconolactonaseQ9X0N8Details
Uracil phosphoribosyltransferaseQ9WZI0Details
Alpha-L-fucosidase, putativeQ9WYE2Details
Release factor glutamine methyltransferaseQ9WYV8Details
Ribosomal RNA small subunit methyltransferase HQ9WZX6Details
Protein-L-isoaspartate O-methyltransferaseQ56308Details
Alpha-glucosidaseO33830Details
Riboflavin biosynthesis proteinQ9WZW1Details
4-hydroxy-tetrahydrodipicolinate reductaseQ9X1K8Details
Probable butyrate kinase 2Q9X278Details
Mannoside ABC transport system, sugar-binding proteinQ9X0V0Details
Transcriptional regulator, IclR familyQ9WXS0Details
Putative L-rhamnose mutarotaseQ9X0F9Details
Aminotransferase, putativeQ9X0L5Details
Putative deoxyribonuclease YcfHQ9WZD5Details
Purine nucleoside phosphorylaseQ9X1T2Details
LaminarinaseQ9WXN1Details
Bifunctional purine biosynthesis protein PurHQ9X0X6Details
L-allo-threonine aldolaseQ9X266Details
tRNA-dihydrouridine synthaseQ9WXV1Details
Oxidoreductase, short chain dehydrogenase/reductase familyQ9WYS2Details
Alcohol dehydrogenase, iron-containingQ9X022Details
NADH-dependent butanol dehydrogenase AQ9WZS7Details
Oxidoreductase, aldo/keto reductase familyQ9X0A2Details
Ribose 5-phosphate isomerase BQ9X0G9Details
Uncharacterized proteinQ9X0P2Details
Peptide deformylaseP96113Details
Fatty acid-binding protein TM_1468Q9X1H9Details
Endo-1,4-beta-xylanase AQ60037Details
50S ribosomal protein L4P38516Details
Beta-fructosidaseO33833Details
Signal recognition particle receptor FtsYQ9WZ40Details
N utilization substance protein B homologQ9X286Details
Glycerol uptake operon antiterminator regulatory proteinQ9X1F0Details
Putative ribosome biogenesis GTPase RsgAQ9X242Details
Rod shape-determining protein MreBQ9WZ57Details
EndoglucanaseQ9X0D8Details
5-methyltetrahydrofolate S-homocysteine methyltransferaseQ9WYA5Details
Sensor histidine kinaseQ9X180Details
50S ribosomal protein L11P29395Details