Evidence for lateral gene transfer between Archaea and bacteria from genome sequence of Thermotoga maritima.
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Nelson KE, Clayton RA, Gill SR, Gwinn ML, Dodson RJ, Haft DH, Hickey EK, Peterson JD, Nelson WC, Ketchum KA, McDonald L, Utterback TR, Malek JA, Linher KD, Garrett MM, Stewart AM, Cotton MD, Pratt MS, Phillips CA, Richardson D, Heidelberg J, Sutton GG, Fleischmann RD, Eisen JA, White O, Salzberg SL, Smith HO, Venter JC, Fraser CM
Evidence for lateral gene transfer between Archaea and bacteria from genome sequence of Thermotoga maritima.
Nature. 1999 May 27;399(6734):323-9.
- PubMed ID
- 10360571 [ View in PubMed]
- Abstract
The 1,860,725-base-pair genome of Thermotoga maritima MSB8 contains 1,877 predicted coding regions, 1,014 (54%) of which have functional assignments and 863 (46%) of which are of unknown function. Genome analysis reveals numerous pathways involved in degradation of sugars and plant polysaccharides, and 108 genes that have orthologues only in the genomes of other thermophilic Eubacteria and Archaea. Of the Eubacteria sequenced to date, T. maritima has the highest percentage (24%) of genes that are most similar to archaeal genes. Eighty-one archaeal-like genes are clustered in 15 regions of the T. maritima genome that range in size from 4 to 20 kilobases. Conservation of gene order between T. maritima and Archaea in many of the clustered regions suggests that lateral gene transfer may have occurred between thermophilic Eubacteria and Archaea.
DrugBank Data that Cites this Article
- Polypeptides
Name UniProt ID L-lactate dehydrogenase P16115 Details 6-phospho-beta-glucosidase BglT Q9X108 Details Thymidylate synthase ThyX Q9WYT0 Details Chemotaxis protein CheA Q56310 Details 4-hydroxy-tetrahydrodipicolinate synthase Q9X1K9 Details Histidinol-phosphate aminotransferase Q9X0D0 Details Holliday junction ATP-dependent DNA helicase RuvB Q56313 Details N-(5'-phosphoribosyl)anthranilate isomerase Q56320 Details Bifunctional PGK/TIM P36204 Details 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase Q9X112 Details 4-alpha-glucanotransferase P80099 Details Polyamine aminopropyltransferase Q9WZC2 Details Aminomethyltransferase Q9WY54 Details Phospho-2-dehydro-3-deoxyheptonate aldolase Q9WYH8 Details Cell division protein FtsZ O08398 Details 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Q9X1B3 Details GTPase Der Q9X1F8 Details Phosphopantetheine adenylyltransferase Q9WZK0 Details 6-phosphogluconolactonase Q9X0N8 Details Uracil phosphoribosyltransferase Q9WZI0 Details Alpha-L-fucosidase, putative Q9WYE2 Details Release factor glutamine methyltransferase Q9WYV8 Details Ribosomal RNA small subunit methyltransferase H Q9WZX6 Details Protein-L-isoaspartate O-methyltransferase Q56308 Details Alpha-glucosidase O33830 Details Riboflavin biosynthesis protein Q9WZW1 Details 4-hydroxy-tetrahydrodipicolinate reductase Q9X1K8 Details Probable butyrate kinase 2 Q9X278 Details Mannoside ABC transport system, sugar-binding protein Q9X0V0 Details Transcriptional regulator, IclR family Q9WXS0 Details Putative L-rhamnose mutarotase Q9X0F9 Details Aminotransferase, putative Q9X0L5 Details Putative deoxyribonuclease YcfH Q9WZD5 Details Purine nucleoside phosphorylase Q9X1T2 Details Laminarinase Q9WXN1 Details Bifunctional purine biosynthesis protein PurH Q9X0X6 Details L-allo-threonine aldolase Q9X266 Details tRNA-dihydrouridine synthase Q9WXV1 Details Oxidoreductase, short chain dehydrogenase/reductase family Q9WYS2 Details Alcohol dehydrogenase, iron-containing Q9X022 Details NADH-dependent butanol dehydrogenase A Q9WZS7 Details Oxidoreductase, aldo/keto reductase family Q9X0A2 Details Ribose 5-phosphate isomerase B Q9X0G9 Details Uncharacterized protein Q9X0P2 Details Peptide deformylase P96113 Details Fatty acid-binding protein TM_1468 Q9X1H9 Details Endo-1,4-beta-xylanase A Q60037 Details 50S ribosomal protein L4 P38516 Details Beta-fructosidase O33833 Details Signal recognition particle receptor FtsY Q9WZ40 Details N utilization substance protein B homolog Q9X286 Details Glycerol uptake operon antiterminator regulatory protein Q9X1F0 Details Putative ribosome biogenesis GTPase RsgA Q9X242 Details Rod shape-determining protein MreB Q9WZ57 Details Endoglucanase Q9X0D8 Details 5-methyltetrahydrofolate S-homocysteine methyltransferase Q9WYA5 Details Sensor histidine kinase Q9X180 Details 50S ribosomal protein L11 P29395 Details