The primary structure of a membrane-associated phospholipase A2 from human spleen.

Article Details

Citation

Kanda A, Ono T, Yoshida N, Tojo H, Okamoto M

The primary structure of a membrane-associated phospholipase A2 from human spleen.

Biochem Biophys Res Commun. 1989 Aug 30;163(1):42-8.

PubMed ID
2775276 [ View in PubMed
]
Abstract

The complete primary structure of membrane-associated phospholipase A2 purified from a human splenic membrane fraction was determined by sequence analysis of the peptides generated by lysyl endopeptidase and Staphylococcus aureus V8 protease cleavage. The enzyme consists of 124 amino acid residues corresponding to a molecular weight of 13,904. The primary structure reveals the characteristics of Group II phospholipases A2 and a large ratio of basic amino acid residues to acidic ones, that ratio being 3.4 : 1.

DrugBank Data that Cites this Article

Polypeptides
NameUniProt ID
Phospholipase A2, membrane associatedP14555Details