The efficacy and safety of cefovecin in the treatment of feline abscesses and infected wounds.

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Stegemann MR, Sherington J, Passmore C

The efficacy and safety of cefovecin in the treatment of feline abscesses and infected wounds.

J Small Anim Pract. 2007 Dec;48(12):683-9. Epub 2007 Aug 23.

PubMed ID
17725587 [ View in PubMed
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Abstract

OBJECTIVES: To determine the efficacy and safety of cefovecin for the treatment of bacterial abscesses and wounds in cats at clinics in Germany, France, Spain and the UK. METHOD: Cats with abscesses or wounds were enrolled. Cats (217) were randomised to treatment with either cefovecin administered by subcutaneous injection at 14 day intervals or amoxicillin/clavulanic acid as twice-daily oral tablets for 14 days. Treatment courses were repeated at 14 day intervals, when deemed necessary. Clinicians assessing lesions were masked to treatment allocation. Only animals with a confirmed pretreatment bacterial pathogen were included in the efficacy analysis. Cases were evaluated 28 days after initiation of the final course of treatment. RESULTS: Cefovecin was as efficacious as amoxicillin/clavulanic acid, and efficacy was 100 per cent for both treatments. CLINICAL SIGNIFICANCE: Cefovecin, administered as a single subcutaneous injection repeated at 14 day intervals as required, was shown to be as efficacious as oral amoxicillin/clavulanic acid in the treatment of abscesses/wounds in cats.

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