The international reference preparation of hygromycin B.
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Davidson I, Hebert CN
The international reference preparation of hygromycin B.
Bull World Health Organ. 1966;35(6):933-43.
- PubMed ID
- 5298042 [ View in PubMed]
- Abstract
The Central Veterinary Laboratory, Weybridge, England, was requested by the WHO Expert Committee on Biological Standardization to obtain suitable material for an international reference preparation of hygromycin B and to arrange a collaborative assay. A batch of 150 g of a highly purified hygromycin B was assayed in eleven laboratories in nine countries against the hygromycin B standard of a commercial manufacturer. On the basis of the results obtained, the material has been established as the International Reference Preparation of Hygromycin B and the International Unit for Hygromycin B has been defined as the activity contained in 0.0008928 mg of the International Reference Preparation of Hygromycin B.
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